News

An interesting workshop entitled “Multi-centre study of home-cage physical activity of C57BL/6 mice and their responses to microenvironmental conditions during consecutive cycles of bi-weekly housing change-outs” has been organized at the next Felasa in Marseilles.

In this seminar results of a multi-centre study into the effects of changes in the internal cage milieu between (bi-weekly) cage changes on home-cage physical activity, action radius, and general health of C57BL/6 mice will be presented.  Mice were housed in automated home-cage monitoring systems (DVC®).

The multi-centre design with the same experimental design and defined experimental conditions was used to enable us to tease-out features that replicated across sites from those that were site-specific.  We observed major differences between sexes, with the male effects being more pronounced than female effects. 

A difference that was only partially explained by the difference in biomass between sexes. The current prevailing management routine with bi-weekly cage changes when animals are housed in individually ventilated cages because of concerns about negative impacts with more frequent housing change-outs and the potential threat of ammonia build-up in relation to animal health will be discussed.

Presenters will:

• introduce the need for automated home-housing systems, especially during the pandemic issues, tying this into the need to really understand the normal behaviors and activities of the animals.
• Presentation of the study: how it was set up and what were the outstanding questions needing to be answered, by how this was constructed (brief reviews of the historical issues with the past publications on animal activities and on animal behaviors with regard to micro-environmental housing concerns).                
• Description of data generated and analysis of the data with recommendations for future studies and needs

A really interesting Workshop with exclusive and innovative data.

If you plan to participate in the next Felasa in Marseilles do not miss this extremely interesting scientific speaking event.

Day: Monday 13th of June

Time: from 13:00 to 14:00

Where: Room Marseilleveyre

Important: The number of places is limited. It is advisable to arrive some minutes before the Workshop starts.
Do not hesitate to contact your Tecniplast Sales person to ask for more details about this interesting Workshop