Aggression in group-housed laboratory male mice is a serious animal welfare concern. Studies have shown that scent marks in the environment can affect the outcome of social interactions between mice.
Regardless of the type of environmental enrichment, complete unnecessary removal of pheromones in scent marked areas due to frequency in cage washing creates a disturbance in male dominance, contributing to higher levels of aggression.
The digital ventilated caging system (DVC®) detects dirty cages and suggests a change “as needed.” Reducing the frequency in cage change decreases the stressors that trigger aggressive behavior, improves animal welfare, has a positive effect on breeding and research outcomes.
DVC® Installed base: More than 25,000 digital cages at more than 50 customers worldwide. For more references directly from DVC® customers, visit 2019 Digital Vivarium Forum